Prolonged pregnancy is considered highrisk as the post term fetus has an. Due to the low estrogen levels, these pregnancies may be prolonged, with dysfunctional labor that may end in cesarean delivery. Genetic predisposition may play a role in prolonging pregnancy 5, 7. Placental sulphatase deficiency for example, is a rare xlinked recessive. Identified risk factors include increasing maternal age, obesity, nulliparity, prior postterm delivery, male fetal sex, placental sulfatase deficiency and fetal anecephaly 1, 345. A pregnancy with placental sulfatase deficiency was suspected when a 36yearold patient at 41 weeks of gestation was found to have extremely low uri. Sulfatase deficiency is probably a congenital, sexspecific, xlinked placental enzyme defect.
Postterm pregnancy is a pregnancy that lasts longer than 42 weeks. Guidelines for the management of postterm pregnancy. Longterm effects of radioiodine in toxic multinodular goitre. Who is at risk for prolonged and postterm pregnancy. Pdf placental steroid sulphatase deficiency ssd is an xlinked inborn error. Maternal obesity, length of gestation, risk of postdates pregnancy and spontaneous onset of labour at term. Placental sulfatase deficiency placental sulfatase deficiency is a rare x. Postterm pregnancy causes and risks birth injury guide. Postmature is reserved for the pathologic syndrome in which the fetus experiences placental insufficiency and resultant iugr. Management of postterm pregnancy practice guidelines.
Definition postterm pregnancy, prolonged pregnancy. Placental sulfatase deficiency placental sulfatase deficiency is a rare xlinked recessive. It may be associated with failed induction of labor and prolonged labor. Scribd is the worlds largest social reading and publishing site. Placental sulfatase deficiency definition of placental. Male sex also has been associated with prolongation of pregnancy 6. That is two weeks past the normal 40week gestation period. Prolonged pregnancy is defined as lasting beyond 287 days, or 41 weeks, since the.
Prolonged pregnancy an overview sciencedirect topics. Decreased sulfatase activity in the placenta, fibroblast, erythrocytes, lymphocytes or leukocytes of affected individuals. Rarely, postterm pregnancy may be associated with placental sulfatase deficiency or fetal anencephaly. Placental sulfatase deficiency, fetal anencephaly, and male sex have been associated with prolongation of pregnancy, and genetic predisposition also may play a role. Development of ichthyosis in male infants at 2 to 3. Post term pregnancy is associated with an increased risk of fetal and neonatal. Since a postterm pregnancy is linked with both fetal and maternal health complications, doctors usually do everything they can to ensure that an infant is delivered as close to the due date as possible.